Vancomycin-resistant enterococci among haemodialysis patients in Portugal: prevalence and molecular characterization of resistance, virulence and clonality.

نویسندگان

  • Susana Correia
  • Pedro Ponce
  • Daniela Jones-Dias
  • Manuela Caniça
  • Gilberto Igrejas
  • Patrícia Poeta
چکیده

INTRODUCTION Vancomycin-resistant enterococci (VRE) among haemodialysis patients has increased rapidly and, to date, there is no report of this incidence in Portugal. METHODS A total of 121 faecal samples were collected from haemodialysis patients, and then tested for VRE. Antimicrobial resistance, virulence and multilocus sequence typing (MLST) were studied. RESULTS VRE prevalence was 3.3%. Three VRE isolates, Enterococcus faecium, Enterococcus faecalis and Enterococcus raffinosus, were multi-resistant and vanA-positive. E. faecium and E. faecalis belonged to CC17 and CC2, respectively. CONCLUSION Haemodialysis patients in Portugal are colonized with virulent, multi-resistant enterococci from high-risk clonal complexes, representing a public health concern.

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عنوان ژورنال:
  • Enfermedades infecciosas y microbiologia clinica

دوره 32 3  شماره 

صفحات  -

تاریخ انتشار 2014